|
| Status |
Public on Nov 20, 2019 |
| Title |
Genome-wide mapping of SET-Nup214, mutant NPM1 (NPM1c), and CRM1-binding sites in human leukemia or mouse ES cell lines |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We used ChIP-seq to examine the genome-wide binding of CRM1, SET-Nup214, and NPM1c in leukemia cell lines. Our analysis revealed that CRM1, SET-Nup214, and NPM1c are preferentially targeted to HOX cluster regions.
|
| |
|
| Overall design |
chromatin immunoprecipitation
|
| |
|
| Contributor(s) |
Oka M, Yoneda Y, Nogami J, Maehara K, Harada A, Ohkawa Y |
| Citation(s) |
31755865 |
| Submission date |
Mar 07, 2019 |
| Last update date |
Nov 25, 2019 |
| Contact name |
Masahiro Oka |
| Organization name |
National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)
|
| Lab |
Laboratory of Nuclear Transport Dynamics
|
| Street address |
7-6-8 Saito-Asagi
|
| City |
Ibaraki |
| State/province |
Osaka |
| ZIP/Postal code |
567-0085 |
| Country |
Japan |
| |
|
| Platforms (2) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
| GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
|
| Samples (32)
|
|
| Relations |
| BioProject |
PRJNA525993 |
| SRA |
SRP187841 |
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