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Series GSE129296 Query DataSets for GSE129296
Status Public on Mar 03, 2021
Title Expression data from microglia in Abeta and TAU mouse models of Alzheimer Disease
Organism Mus musculus
Experiment type Expression profiling by array
Summary Microglia activation is a hallmark in Alzheimer Disease. Non-active and Active microglia were isolated from young and aged WT mice and before- and after- pathology mouse models of Alzheimer Disease.
Microarray analysis was used to determine the global gene expression programe in microglia during pathological (Abeta or TAU pathology) versus control state.
 
Overall design Cortical plus hippocampal microglia (CD45+ and CD11b+) were isolated from WT, APP and TAU mice at 3 and 9-12 month-old. Active microglia were isolated as Clec7a+ microglia.
 
Contributor(s) Romero-Molina C, Virtudes Sanchez-Mico M, Vizuete M, Vitorica J
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Submission date Apr 03, 2019
Last update date Mar 05, 2021
Contact name Carmen Romero-Molina
E-mail(s) cromero15@us.es
Phone 955923052
Organization name University of Seville. Institute of Biomedicine of Seville
Department Faculty of Pharmacy. Biochemistry and Molecular Biology
Lab 111
Street address Profesor Garcia Gonzalez, 2
City Seville
State/province Seville
ZIP/Postal code 41012
Country Spain
 
Platforms (1)
GPL23038 [Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay)
Samples (23)
GSM3704171 Microglia WT 3m, biological rep1
GSM3704172 Microglia WT 3m, biological rep2
GSM3704173 Microglia WT 3m, biological rep3
Relations
BioProject PRJNA530765

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE129296_RAW.tar 25.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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