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| Status |
Public on May 01, 2020 |
| Title |
Recombinant humant thrombomodulin treatment against endotoxemia-induced acute respiratory distress syndrome (ARDS). |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We made LPS induced ARDS model mice, and determined the effect of recombinant human thrombomodulin against ARDS.
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| Overall design |
Following 16-h starvation, mice were intraperitoneally injected with LPS (20 mg/kg; MilliporeSigma, Burlington, MA), and in some assays, with saline or recombinant human thrombomodulin (rhTM; Asahi Kasei Pharma Corporation, Tokyo, Japan) at 3 and 24 h post-LPS injection. Total RNA was extracted from mouse lung 30h after LPS injection.
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| Contributor(s) |
Okada H |
| Citation(s) |
32497259 |
| Submission date |
Apr 26, 2019 |
| Last update date |
Jun 09, 2020 |
| Contact name |
Hideshi Okada |
| E-mail(s) |
hideshiokada@gmail.com
|
| Phone |
+81-58-230-6448
|
| Organization name |
Gifu University Graduate School of Medicine
|
| Department |
Emergency and Disaster Medicine
|
| Street address |
1-1 Yanagido
|
| City |
Gifu |
| ZIP/Postal code |
501-1194 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (6)
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| GSM3736822 |
Saline treated mouse 1 30 hours after LPS injected |
| GSM3736823 |
Saline treated mouse 2 30 hours after LPS injected |
| GSM3736824 |
Saline treated mouse 3 30 hours after LPS injected |
| GSM3736825 |
Recombinant human thrombomodulin treated mouse 1 30 hours after LPS administration |
| GSM3736826 |
Recombinant human thrombomodulin treated mouse 2 30 hours after LPS administration |
| GSM3736827 |
Recombinant human thrombomodulin treated mouse 3 30 hours after LPS administration |
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| Relations |
| BioProject |
PRJNA539896 |
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