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| Status |
Public on Oct 06, 2020 |
| Title |
A single-cell survey of cellular hierarchy in acute myeloid leukemia |
| Organisms |
Homo; Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We applied Micro-well seq, a high-throughput and low-costing single-cell RNA platform, to 40 patients with 3 healthy donors. We identified a key subgroup and characterized its gene expression pattern from diagnosis to relapse, revealing its features in refractory patients. In addition, we combined next generation and SMRT sequencing to track the clonal evolution.
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| |
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| Overall design |
Expression profiling of de novo AML by Microwell-seq
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| |
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| Contributor(s) |
Wu J, Xiao Y, Sun H |
| Citation(s) |
32977829 |
| Submission date |
May 06, 2019 |
| Last update date |
Mar 13, 2024 |
| Contact name |
Junqing Wu |
| E-mail(s) |
wujunqing@zju.edu.cn
|
| Organization name |
Zhejiang University
|
| Street address |
Yuhangtang Road 866
|
| City |
Hangzhou |
| ZIP/Postal code |
310058 |
| Country |
China |
| |
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| Platforms (2) |
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| Samples (49)
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| Relations |
| BioProject |
PRJNA541288 |
| SRA |
SRP195575 |
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