NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE130913 Query DataSets for GSE130913
Status Public on Oct 27, 2021
Title RNA-seq in male and female mouse liver for two mouse strains: C57BL/6J and CAST/EiJ.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Sequencing files provided here are mouse liver RNA-seq in two mouse strains: C57BL/6J and CAST/EiJ. This is part of a larger study published in PLoS Genetics (2021) "Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model" that includes DNase-seq and H3K27ac ChIP-seq in mouse liver from the same two strains. This allows us to identify strain-shared ("core") and strain-unique sex-biased genes and enhancers.
 
Overall design RNA-seq in male and female mouse liver, n=5 biological replicates per sex and per strain
 
Contributor(s) Matthews BJ, Waxman DJ
Citation(s) 34752452
NIH grant(s)
Grant ID Grant title Affiliation Name
R01 DK121998 Growth Hormone Regulation of Sex Differences in Liver Metabolism BOSTON UNIVERSITY CHARLES RIVER CAMPUS DAVID J WAXMAN
Submission date May 08, 2019
Last update date Nov 12, 2021
Contact name David J. Waxman
E-mail(s) djw@bu.edu
Organization name Boston University
Department Department of Biology and Bioinformatics Program
Street address 5 Cummington Mall
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (20)
GSM3756116 Male_B6_PolyA_RNA_Repl1_G164_M1
GSM3756117 Male_B6_PolyA_RNA_Repl2_G164_M2
GSM3756118 Male_B6_PolyA_RNA_Repl3_G164_M3
This SubSeries is part of SuperSeries:
GSE130914 Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model
Relations
BioProject PRJNA542067
SRA SRP197259

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE130913_B6_EdgeR.txt.gz 2.9 Mb (ftp)(http) TXT
GSE130913_CAST_EdgeR.txt.gz 2.8 Mb (ftp)(http) TXT
GSE130913_FPKM_perGene.txt.gz 2.5 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap