|
| Status |
Public on Oct 29, 2019 |
| Title |
RNA sequencing data describing transcriptional changes in aorta of ApoE-/- mice after alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This manuscript is a companion paper to Ulleryd M.U. et al (1). Data shown here include RNA sequencing data from whole aorta of ApoE-/- mice treated with the alpha 7 nicotinic acetylcholine receptor (α7nAChR) agonist AZ6983 for 8 weeks using subcutaneously implanted osmotic minipumps. 1. Ulleryd MA, Mjornstedt F, Panagaki D, Yang LJ, Engevall K, Gutierrez S, et al. Stimulation of alpha 7 nicotinic acetylcholine receptor (α7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells Re-submitted. 2019.
|
| |
|
| Overall design |
ApoE-/- mice were treated with alpha 7 nicotinic acetylcholine receptor (α7nAChR) agonist AZ6983 or vehicle for 8 weeks using subcutaneously implanted osmotic minipumps. RNA from whole aorta were extracted and used for RNA sequencing analysis. n=6 per group.
|
| |
|
| Contributor(s) |
Ulleryd MA, Mjörnstedt F, Panagaki D, Yang LJ, Engevall K, Gutierrez S, Wang Y, Gan L, Nilsson H, Michaelsson E, Johansson ME |
| Citation(s) |
32258279 |
| Submission date |
May 14, 2019 |
| Last update date |
Apr 13, 2020 |
| Contact name |
Maria E Johansson |
| E-mail(s) |
maria.e.johansson@neuro.gu.se
|
| Organization name |
University of Gothenburg
|
| Department |
Physiology
|
| Street address |
Medicinaregatan 11
|
| City |
Gothenburg |
| ZIP/Postal code |
405 30 |
| Country |
Sweden |
| |
|
| Platforms (1) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA542796 |
| SRA |
SRP198349 |
Less...
More...