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| Status |
Public on Dec 27, 2019 |
| Title |
Age-related transcriptional modules and TF-miRNA-mRNA interactions in neonatal and infant human thymus [mRNA] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The human thymus shows a transient involution along the neonatal period and starts a continuous process of decline between the 1st and 2nd years. The immune alterations associated to thymic aging in humans have been extensively investigated, but the genomic mechanisms underlying this process remain largely unknown. Here we conducted a temporal gene co-expression network analysis in the newborn and infant thymic tissue aiming to identify transcriptional modules associated to age.
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| Overall design |
Temporal gene co-expression network analysis and miRNA analysis in the newborn and infant thymic tissue aiming to identify transcriptional modules associated to age.
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| Contributor(s) |
Bertonha FB, Bando SY, Ferreira LR, Chaccur P, Vinhas C, Zerbini MC, Carneiro-Sampaio MM, Moreira-Filho CA |
| Citation(s) |
32294112 |
| Submission date |
May 14, 2019 |
| Last update date |
Apr 16, 2020 |
| Contact name |
Carlos Alberto Moreira-Filho |
| E-mail(s) |
carlos.moreira@hc.fm.usp.br
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| Phone |
55-11-3061-8449
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| Organization name |
Faculdade de Medicina da Universidade de Sao Paulo
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| Department |
Departments of Pediatrics
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| Lab |
LIM36
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| Street address |
Av. Dr. Eneas Carvalho de Aguiar 647
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| City |
Sao Paulo |
| State/province |
SP |
| ZIP/Postal code |
05403-900 |
| Country |
Brazil |
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| Platforms (1) |
| GPL13497 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (50)
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| This SubSeries is part of SuperSeries: |
| GSE131242 |
Age-related transcriptional modules and TF-miRNA-mRNA interactions in neonatal and infant human thymus |
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| Relations |
| BioProject |
PRJNA542875 |
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