Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
Summary
Inhibition of ARID3a by shRNA in hemin-induced K562 cells results in significant decrease of erythroid specific lineage factors and alpha-globin genes.
Overall design
Differential expression analysis of K562 cells treated with hemin and hemin + ARID3a shRNA.
For ATAC-seq samples, AL and BH represent the KO or "--" and BH and P represent wild type or "++" clones.
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