|
| Status |
Public on Apr 08, 2020 |
| Title |
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Genome variation profiling by high throughput sequencing
Expression profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Citation(s) |
32393766, 32989253 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P50 CA168504 |
BET Bromodomain proteins as Novel Therapeutic Targets in Triple Negative Breast |
DANA-FARBER CANCER INSTITUTE |
KORNELIA POLYAK |
| R35 CA197623 |
Targeting intratumor heterogeneity in breast cancer |
DANA-FARBER CANCER INSTITUTE |
KORNELIA POLYAK |
| U54 CA193461 |
Project 3: Single Cell Measures of Intratumor Diversity for Optimal Breast Cancer Therapy |
DANA-FARBER CANCER INSTITUTE |
KORNELIA POLYAK |
| F30 CA228208 |
Optimal BET inhibitor combination therapies in triple negative breast cancer |
HARVARD UNIVERSITY (MEDICAL SCHOOL) |
Jennifer Yawei Ge |
|
| Submission date |
May 30, 2019 |
| Last update date |
Oct 30, 2020 |
| Contact name |
Kornelia Polyak |
| E-mail(s) |
kornelia_polyak@dfci.harvard.edu
|
| Phone |
617-632-2106
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Medical Oncology
|
| Lab |
Polyak
|
| Street address |
450 Brookline Ave
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (3) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
|
| Samples (223)
|
|
| This SuperSeries is composed of the following SubSeries:
|
| GSE131977 |
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer [Barcode] |
| GSE131980 |
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer [Exome] |
| GSE131983 |
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer [RNA-Seq] |
| GSE131984 |
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer [scRNA-Seq] |
|
| Relations |
| BioProject |
PRJNA545501 |
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