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| Status |
Public on Nov 30, 2008 |
| Title |
(AKR/J x PyMT)F1 versus (DBA/2J x PyMT)F1 tumor expression data |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from mouse tumor tissues
Keywords: Basal transcription profiles
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| Overall design |
Mammary tumors from adult F1 animals from (AKR/J x PyMT) and (DBA/2J x PyMT) outcrosses was collected and arrayed on Affymetrics chip to identify basal differences in gene expression between the different genotypes
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| |
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| Contributor(s) |
Hunter KW |
| Citation(s) |
19118016 |
| Submission date |
Oct 16, 2008 |
| Last update date |
Jan 08, 2019 |
| Contact name |
Kent Hunter |
| E-mail(s) |
hunterk@mail.nih.gov
|
| Organization name |
National Cancer Institute
|
| Department |
Center for Cancer Research
|
| Lab |
Laboratory of Cancer Biology and Genetics
|
| Street address |
37/4048 37 Convent Drive
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892-4264 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL339 |
[MOE430A] Affymetrix Mouse Expression 430A Array |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE13231 |
The effect of inherited polymorphism on prognostic gene expression signatures |
|
| Relations |
| BioProject |
PRJNA114039 |
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