|
| Status |
Public on Oct 29, 2020 |
| Title |
Chromatin response to hypoxia in MCF7 cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Oxygen is essential for cell growth, however in tumours quick growth can cause hypoxic conditions. To determine the changes in the chromatin landscape in response to hypoxia in breast cancer we have performed ATAC-seq dugin normoxia and hypoxia.
|
| |
|
| Overall design |
Biological replicates with one or two technical replicates were grown for 48 hours in hypoxic or normoxic conditions before ATAC-seq.
|
| |
|
| Contributor(s) |
Downes DJ, Miar A, Harris A |
| Citation(s) |
33115807 |
| Submission date |
Jun 26, 2019 |
| Last update date |
Oct 31, 2020 |
| Contact name |
Damien Downes |
| E-mail(s) |
damien.downes@ndcls.ox.ac.uk
|
| Phone |
01865222374
|
| Organization name |
The University of Oxford
|
| Department |
MRC Weatherall Institute of Medicine
|
| Street address |
John Radcliffe Hospital
|
| City |
Headington |
| State/province |
Oxfordshire |
| ZIP/Postal code |
OX3 9DU |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (11)
|
|
| Relations |
| BioProject |
PRJNA551124 |
| SRA |
SRP212099 |
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