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Series GSE133527 Query DataSets for GSE133527
Status Public on Jan 12, 2020
Title miR-221-3p drives the Shift of M2-Macrophage to a Pro-Inflammatory Function by Modulating JAK3/STAT3 Signaling and is Increased in Rheumatoid Arthritis
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We performed a transcriptome analysis of M2 macrophages generated in vitro from monocytes isolated from peripheral blood of healthy donors, and studied the effect of miR-221-3p mimic transfection and stimulation with LPS.
Overall design miR-221-3p mimic was added to cultured macrophages for 63.5 hours, prior to stimulation with 100 ng/ml LPS for 8.5 hours.
Contributor(s) Quero L, Kyburz D
Citation(s) 32047494
Submission date Jun 28, 2019
Last update date Feb 18, 2020
Contact name Diego Kyburz
Organization name University of Basel
Department Biomedicine
Lab Experimental rheumatology
Street address Petersplatz 4
City Basel
ZIP/Postal code 4031
Country Switzerland
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (20)
GSM3911300 ctrl_81
GSM3911301 ctrl_85
GSM3911302 ctrl_95
BioProject PRJNA551688
SRA SRP212629

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE133527_gene_counts.tsv.gz 647.9 Kb (ftp)(http) TSV
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Raw data are available in SRA
Processed data are available on Series record

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