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Series GSE134962 Query DataSets for GSE134962
Status Public on Sep 10, 2019
Title Enhancer Profiling Reveals Regulators of Skeletal Muscle Identity and Reprogramming [ATAC-seq]
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Chromatin immunoprecipitation sequencing of H3K4me2, H3K27ac as well as, ATACseq and RNA-seq reveals regulatory landscapes across different muscle groups, as well as in response to chronic exercise or muscle PGC1a overexpression. This work defines the unique enhancer repetoire of skeletal muscle in vivo and reveals that highly divergent exercise-induced or PGC1a-driven epigenomic programs direct partially convergent transcriptional networks.
 
Overall design Genome-wide maps of chromatin state in different muscles from sedentary mice
 
Contributor(s) Barish G, Ramachandran K
Citation(s) 31589602
Submission date Jul 26, 2019
Last update date Nov 04, 2019
Contact name Grant D. Barish
Organization name Northwestern University
Department Medicine
Street address 303 E Superior Street
City Chicago
State/province IL
ZIP/Postal code 60611
Country USA
 
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (4)
GSM3981671 quad_ATAC
GSM3981672 soleus_ATAC
GSM3981673 edl_ATAC
This SubSeries is part of SuperSeries:
GSE123879 Enhancer Profiling Reveals Regulators of Skeletal Muscle Identity and Reprogramming
Relations
BioProject PRJNA556888
SRA SRP216531

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE134962_RAW.tar 2.7 Gb (http)(custom) TAR (of BEDGRAPH, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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