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| Status |
Public on Sep 01, 2009 |
| Title |
Rat lung gene expression during acute pulmonary embolism |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Rats were given pulmonary embolism by i.v. injection of 25 micron polystyrene microspheres or 0.01% Tween20 solution as vehicle control
Embolism of microspheres is irreversible and causes dose dependent pulmonary hypertension
Keywords: time course and dose response
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| Overall design |
Rats received one of three treatments: 0.15 ml/100 grams weight of 0.01% Tween20 as "vehicle" control; 0.10 ml/100 grams of 10% microsphere suspension in 0.01% Tween20 = 1.3 million/100 grams = "PE1.3" dose; 0.15 ml/100 grams of 10% microspheres = 2.0 million/100 grams = "PE2.0" dose; rats were euthanized at either 2 hours or 18 hours after treatment
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| Contributor(s) |
Zagorski J, Kline JA |
| Citation(s) |
27435598 |
| Submission date |
Nov 08, 2008 |
| Last update date |
Aug 11, 2017 |
| Contact name |
John Zagorski |
| E-mail(s) |
john.zagorski@carolinas.org, j_zagorski@hotmail.com
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| Phone |
704-355-3663
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| Organization name |
Carolinas Medical Center
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| Department |
Emergency Medicine
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| Lab |
Cannon Research Center
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| Street address |
1542 Garden Terrace, 301
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| City |
Charlotte |
| State/province |
NC |
| ZIP/Postal code |
28203 |
| Country |
USA |
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| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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| Samples (22)
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| GSM341273 |
2 hour vehicle control rat, lung tissue, biological rep1 |
| GSM341274 |
2 hour vehicle control rat, lung tissue, biological rep2 |
| GSM341275 |
2 hour vehicle control rat, lung tissue, biological rep3 |
| GSM341276 |
2 hour PE1.3 embolized rat, lung tissue, biological rep1 |
| GSM341277 |
2 hour PE1.3 embolized rat, lung tissue, biological rep2 |
| GSM341278 |
2 hour PE1.3 embolized rat, lung tissue, biological rep3 |
| GSM341279 |
2 hour PE1.3 embolized rat, lung tissue, biological rep4 |
| GSM341280 |
2 hour PE2.0 embolized rat, lung tissue, biological rep1 |
| GSM341281 |
2 hour PE2.0 embolized rat, lung tissue, biological rep2 |
| GSM341282 |
2 hour PE2.0 embolized rat, lung tissue, biological rep3 |
| GSM341283 |
2 hour PE2.0 embolized rat, lung tissue, biological rep4 |
| GSM341284 |
18 hour vehicle control rat, lung tissue, biological rep1 |
| GSM341285 |
18 hour vehicle control rat, lung tissue, biological rep2 |
| GSM341286 |
18 hour vehicle control rat, lung tissue, biological rep3 |
| GSM341287 |
18 hour PE1.3 embolized rat, lung tissue, biological rep1 |
| GSM341288 |
18 hour PE1.3 embolized rat, lung tissue, biological rep2 |
| GSM341289 |
18 hour PE1.3 embolized rat, lung tissue, biological rep3 |
| GSM341290 |
18 hour PE1.3 embolized rat, lung tissue, biological rep4 |
| GSM341291 |
18 hour PE2.0 embolized rat, lung tissue, biological rep1 |
| GSM341292 |
18 hour PE2.0 embolized rat, lung tissue, biological rep2 |
| GSM341293 |
18 hour PE2.0 embolized rat, lung tissue, biological rep3 |
| GSM341294 |
18 hour PE2.0 embolized rat, lung tissue, biological rep4 |
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| Relations |
| BioProject |
PRJNA110709 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE13535_RAW.tar |
63.2 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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