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Status |
Public on Jan 31, 2020 |
Title |
RNAseq of renal CD64+CD11b+F4/80hi from adult mice after cisplatin-induced acute kidney injury |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We use bulk RNA sequencing of sorted cells to characterize the gene expression profiles of renal MHCII+/-D11b+F4/80hi cells 72 hours after cisplatin-induced acute kidney injury (AKI). F4/80hi cells are activated after cisplatin induced AKI and start to downregulate MHCII on transcriptional level. Downregulation of MHCII is probably caused by a downregulation/inhibition of its most important transcriptional activator Ciita
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Overall design |
bulk RNA sequencing of sorted murine renal F4/80hi cells before and after cisplatin induced acute kidney injury
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Contributor(s) |
Rambichler S, Salei N, Schraml BU |
Citation(s) |
31932472 |
Submission date |
Aug 17, 2019 |
Last update date |
Jun 10, 2020 |
Contact name |
Barbara Schraml |
E-mail(s) |
barbara.schraml@med.uni-muenchen.de
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Organization name |
LMU Munich
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Street address |
Großhaderner Strasse 9
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City |
Planegg |
ZIP/Postal code |
82152 |
Country |
Germany |
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Platforms (1) |
GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
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Samples (8)
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Relations |
BioProject |
PRJNA560645 |
SRA |
SRP218653 |