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| Status |
Public on Feb 29, 2020 |
| Title |
Rbm24 functions as a critical translational regulator to pretect crystallin proteins accumulation for lens transparency. RNA-seq data of 33 hpf rbm24a-/- and wildtype zebrafish embryo |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This experiment is aimed to compare the transcriptomes of rbm24a mutant and wildtype at 33 hpf. As Rbm24a is an RNA binding protein, this comparation is suitable to obtain information on differential gene expression and alternative splicing. We found that the expression of most of the crystallin genes and many other lens specific genes are down regulated in rbm24a mutant, without changes in splicing patterns.
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| Overall design |
It contains two groups: wildtype and rbm24a-/-. Wildtype was used as control, and each group has three replicates
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| Contributor(s) |
Shao M, Shi D |
| Citation(s) |
32170011 |
| Submission date |
Aug 19, 2019 |
| Last update date |
Apr 13, 2020 |
| Contact name |
Ming Shao |
| E-mail(s) |
shaoming@sdu.edu.cn
|
| Phone |
86 13853136468
|
| Organization name |
Shandong University
|
| Department |
School of Lifesciences
|
| Street address |
27# Shan Da Nan Lu Road
|
| City |
Jinan |
| State/province |
Shandong |
| ZIP/Postal code |
250100 |
| Country |
China |
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| Platforms (1) |
| GPL14875 |
Illumina HiSeq 2000 (Danio rerio) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA560932 |
| SRA |
SRP218847 |
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