|
| Status |
Public on Jan 08, 2020 |
| Title |
Transcriptional profiling of the adult mouse retina in wild-type and Nrl deficient mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We performed mRNA transcriptional profiling of mouse retina in the wild-type and Nrl-null context to determine Nrl-dependent gene expression
We sequenced cDNA libraries made from polyA+ selected RNA from retinas of litter-matched WT and Nrl-/- adult mice at postnatal day 21 (P21) (WT vs Nrl-/-, n=5 and n= 6 resp.)
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| |
|
| Overall design |
Differential mRNA-seq testing of 21-day old wild type (WT) and Nrl-/- mice generated from polyA enriched RNA
|
| Web link |
https://0-doi-org.brum.beds.ac.uk/10.1242/dev.184432
|
| |
|
| Contributor(s) |
Perez-Cervantes C, Nadadur RD, Smith LA, Moskowitz IP |
| Citation(s) |
31915147 |
| Submission date |
Aug 28, 2019 |
| Last update date |
Jan 10, 2020 |
| Contact name |
Ivan Moskowitz |
| E-mail(s) |
imoskowitz@peds.bsd.uchicago.edu
|
| Organization name |
University of Chicago
|
| Department |
Pediatrics, Pathology, and Human Genetics
|
| Street address |
900 E 57th St
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60637 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (11)
|
| GSM4051635 |
IMJCWT1: Wild-type replicate 1 mRNA-seq |
| GSM4051636 |
IMJCWT2: Wild-type replicate 2 mRNA-seq |
| GSM4051637 |
IMJCWT3: Wild-type replicate 3 mRNA-seq |
|
| This SubSeries is part of SuperSeries: |
| GSE136565 |
Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types |
|
| Relations |
| BioProject |
PRJNA562698 |
| SRA |
SRP219918 |
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