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| Status |
Public on Jan 31, 2021 |
| Title |
DNA hydroxy-methylation data of tumor and non-tumor liver (NTL) tissues from Peruvian patients with hepatocellular carcinoma (HCC) |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
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| Summary |
A large fraction of HCC in Peru arises in younger, non-cirrhotic patients. Global DNA hydroxy-methylation analysis of the HCC and NTL tissues demonstrate that hydroxy-methylation conversion interplays with gene expression to enact cell fate determination and cancer cell reprogramming.
We used microarrays to identify hydroxy-methylated CpGs by comparison to Gene Expression Omnibus (GEO) series GSE136319 and GSE136380.
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| Overall design |
HCC patients were treated by anatomic liver resection. Non-tumor liver tissues were obtained from tumour-free margins of resected surgical pieces. Total DNA was isolated from flash-frozen samples for hybridization on Illumina microarrays.
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| Web link |
https://www.oncotarget.com/article/27890/text/
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| Contributor(s) |
Cerapio JP, Pineau P |
| Citation(s) |
33747361 |
| Submission date |
Aug 28, 2019 |
| Last update date |
Mar 23, 2021 |
| Contact name |
Juan Pablo Cerapio |
| E-mail(s) |
jcerapioarroyo@gmail.com, juan-pablo.cerapio-arroyo@inserm.fr
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| Organization name |
CRCT
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| Street address |
Av 2 Hubert Curien
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| City |
Toulouse |
| ZIP/Postal code |
31000 |
| Country |
France |
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| Platforms (1) |
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| Samples (62)
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| GSM4052031 |
Peruvian, HCC Patient, 026 |
| GSM4052032 |
Peruvian, HCC Patient, 034 |
| GSM4052033 |
Peruvian, HCC Patient, 047 |
| GSM4052034 |
Peruvian, HCC Patient, 054 |
| GSM4052035 |
Peruvian, HCC Patient, 068 |
| GSM4052036 |
Peruvian, HCC Patient, 070 |
| GSM4052037 |
Peruvian, HCC Patient, 083 |
| GSM4052038 |
Peruvian, HCC Patient, 088 |
| GSM4052039 |
Peruvian, HCC Patient, 091 |
| GSM4052040 |
Peruvian, HCC Patient, 092 |
| GSM4052041 |
Peruvian, HCC Patient, 093 |
| GSM4052042 |
Peruvian, HCC Patient, 095 |
| GSM4052043 |
Peruvian, HCC Patient, 099 |
| GSM4052044 |
Peruvian, HCC Patient, 100 |
| GSM4052045 |
Peruvian, HCC Patient, 101 |
| GSM4052046 |
Peruvian, HCC Patient, 104 |
| GSM4052047 |
Peruvian, HCC Patient, 106 |
| GSM4052048 |
Peruvian, HCC Patient, 109 |
| GSM4052049 |
Peruvian, HCC Patient, 116 |
| GSM4052050 |
Peruvian, HCC Patient, 117 |
| GSM4052051 |
Peruvian, HCC Patient, 120 |
| GSM4052052 |
Peruvian, HCC Patient, 121 |
| GSM4052053 |
Peruvian, HCC Patient, 179 |
| GSM4052054 |
Peruvian, HCC Patient, 180 |
| GSM4052055 |
Peruvian, HCC Patient, 188 |
| GSM4052056 |
Peruvian, HCC Patient, 190 |
| GSM4052057 |
Peruvian, HCC Patient, 200 |
| GSM4052058 |
Peruvian, HCC Patient, 201 |
| GSM4052059 |
Peruvian, NTL Patient, 004 |
| GSM4052060 |
Peruvian, NTL Patient, 015 |
| GSM4052061 |
Peruvian, NTL Patient, 025 |
| GSM4052062 |
Peruvian, NTL Patient, 026 |
| GSM4052063 |
Peruvian, NTL Patient, 034 |
| GSM4052064 |
Peruvian, NTL Patient, 047 |
| GSM4052065 |
Peruvian, NTL Patient, 054 |
| GSM4052066 |
Peruvian, NTL Patient, 068 |
| GSM4052067 |
Peruvian, NTL Patient, 070 |
| GSM4052068 |
Peruvian, NTL Patient, 083 |
| GSM4052069 |
Peruvian, NTL Patient, 088 |
| GSM4052070 |
Peruvian, NTL Patient, 091 |
| GSM4052071 |
Peruvian, NTL Patient, 092 |
| GSM4052072 |
Peruvian, NTL Patient, 093 |
| GSM4052073 |
Peruvian, NTL Patient, 095 |
| GSM4052074 |
Peruvian, NTL Patient, 099 |
| GSM4052075 |
Peruvian, NTL Patient, 100 |
| GSM4052076 |
Peruvian, NTL Patient, 101 |
| GSM4052077 |
Peruvian, NTL Patient, 104 |
| GSM4052078 |
Peruvian, NTL Patient, 106 |
| GSM4052079 |
Peruvian, NTL Patient, 109 |
| GSM4052080 |
Peruvian, NTL Patient, 116 |
| GSM4052094 |
Peruvian, NTL Patient, 117 |
| GSM4052095 |
Peruvian, NTL Patient, 120 |
| GSM4052096 |
Peruvian, NTL Patient, 121 |
| GSM4052097 |
Peruvian, NTL Patient, 179 |
| GSM4052098 |
Peruvian, NTL Patient, 180 |
| GSM4052099 |
Peruvian, NTL Patient, 188 |
| GSM4052100 |
Peruvian, NTL Patient, 190 |
| GSM4052101 |
Peruvian, NTL Patient, 200 |
| GSM4052102 |
Peruvian, NTL Patient, 201 |
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| Relations |
| BioProject |
PRJNA562836 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE136583_RAW.tar |
1016.7 Mb |
(http)(custom) |
TAR (of IDAT) |
| Processed data included within Sample table |
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