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| Status |
Public on Sep 18, 2019 |
| Title |
Candida albicans Cells: Control vs. BDSF (Cis-2-dodecenoic acid) treatment |
| Organism |
Candida albicans SC5314 |
| Experiment type |
Expression profiling by array
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| Summary |
Cis-2-dodecenoic acid (BDSF), a signalling molecule produced from burkholderia cenocepanic, can prevent C. albicans hyphal and biofilm formation. The mechanism of how BDSF controls C. albicans morphological switch is still unknown. To address this issue, we used DNA microarray method to investigate the changes in gene expression before and after BDSF treatment. Further, screening a mutant library based on microarray data was carried out to find the mutants unresponding to BDSF.
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| Overall design |
Two-condition experiment, control vs. BDSF treatment. Biological replicates: C1 and C2 are control group, B1 and B2 are BDSF treatment group. One replicate per array.
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| Contributor(s) |
Yang D, Weng L |
| Citation(s) |
31947778 |
| Submission date |
Sep 17, 2019 |
| Last update date |
Mar 16, 2020 |
| Contact name |
Dongliang Yang |
| E-mail(s) |
201910006531@njtech.edu.cn
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| Organization name |
Nanjing University of Posts and Telecommunications
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| Department |
Institute of Advanced Materials
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| Street address |
9 wenyuan road, xianlin
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| City |
Nanjing |
| State/province |
Jiangsu |
| ZIP/Postal code |
210046 |
| Country |
China |
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| Platforms (1) |
| GPL27468 |
CapitalBio 8K Candida albicans genome array |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA565899 |
