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| Status |
Public on Oct 16, 2019 |
| Title |
Analysis of differentially expressed genes in intrahepatic HBsAg accumulating mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Search for distinct genes whose expression correlates with IFN⍺ mediated liver injury in HBsAg-Tg mice. IFN treatment induces liver injury from 8 hours post IFN treament, peaking at 24 hours, in HBs transgenic mice and not in the non-transgenic (control) mice
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| Overall design |
snap-frozen liver samples were obtained from groups of four HBsAg-Tg (Tg) and control mice (CTL) sacrificed prior to (0 hour) and 2, 4, 8 and 24 hours after treatment with 5MU/kg of IFN⍺. RNA was analysed from duplicate biological replicates . Groupings A-E correspond to the timepoints 0,2,4,8 and 24 hours.
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| Contributor(s) |
Baudi I, Isogawa M, Onishi M |
| Citation(s) |
33979382 |
| Submission date |
Oct 15, 2019 |
| Last update date |
May 24, 2021 |
| Contact name |
Ian Baudi |
| E-mail(s) |
baudiian@gmail.com
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| Organization name |
Nagoya City University Graduate School of Medical Sciences
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| Department |
Virology
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| Lab |
Virology
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| Street address |
Kawasumi, Mizuho
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| City |
Nagoya |
| State/province |
Aichi |
| ZIP/Postal code |
467-8601 |
| Country |
Japan |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA577721 |
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