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| Status |
Public on Dec 01, 2009 |
| Title |
Dynamic response of annexin A11-associated gene expression to cisplatin treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Based on a time-course study of cisplatin response in ovarian cancer cells with/without suppression of annexin A11 expression using whole genome oligonucleotide microarrays, we identified a set of differentially expressed genes associated with annexin A11 expression and patterns of gene expressions in response to cisplatin exposure.
Keywords: human ovarian cancer cell lines
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| Overall design |
2008 cells (one ovarian cancer cell line) were transfected with ANXA11_RNAi or control_RNAi for 2 days and then treated with 10 µM cisplatin (Sigma) for 0, 8, 16, 24 hours. Total RNA of 8 samples were prepared for gene expression profiling using the Agilent 44K whole genome oligonucleotide microarrays.
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| Contributor(s) |
Zhen Z, Jin S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 10, 2008 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Jin Song |
| E-mail(s) |
jsong20@jhmi.edu
|
| Phone |
4105020419
|
| Fax |
410-502-7882
|
| Organization name |
Johns Hopkins Medical Institutions
|
| Department |
Pathology
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| Lab |
Center for Biomarker Discovery
|
| Street address |
419 N. Caroline Str.
|
| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21231 |
| Country |
USA |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA110297 |
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