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| Status |
Public on Oct 20, 2020 |
| Title |
Gene expression profiles of Dclk1+ and Dclk1- PDAC cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Doublecortin-like kinase 1 (Dclk1) is known as a cancer stem cell marker of pancreatic ductal adenocarcinoma (PDAC). But the functional evidence to define the stem cell activity of these cells within tumors has not been explored. We compared the gene expression profiles of Dclk1-positive and -negative PDACs cells.
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| Overall design |
To determine the molecular characteristics of Dclk1+ PDAC cells, we performed microarray analysis on FACS-sorted Dclk1+ and Dclk1- PDAC cells obtained from Dclk1CreERT2-IRES-EGFP/+; Pdx1-Flp; KrasFSF-G12D/+; Trp53frt/frt (DKPF) mice.
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| Contributor(s) |
Maruno T, Seno H |
| Citation(s) |
33393460 |
| Submission date |
Oct 21, 2019 |
| Last update date |
Jan 19, 2021 |
| Contact name |
Takahisa Maruno |
| E-mail(s) |
maruno@kuhp.kyoto-u.ac.jp
|
| Organization name |
Kyoto university
|
| Department |
Gastroenterology and hepatology
|
| Street address |
54 Syogoin-Kawahara-cho, Sakyo-ku
|
| City |
Kyoto |
| State/province |
Kyoto |
| ZIP/Postal code |
606-8507 |
| Country |
Japan |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA578683 |
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