|
| Status |
Public on Sep 02, 2020 |
| Title |
Gene expression profiling of colorectal cancer cell lines after treatment with talazoparib |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We have performed post-treatment gene expression profiling of cell lines to analyze response mechanisms to PARP inhibition.
|
| |
|
| Overall design |
Four colorectal cancer cell lines were treated with talazoparib at two different concentrations or DMS for control.
|
| |
|
| Contributor(s) |
Sveen A, Eilertsen IA, Lothe RA |
| Citation(s) |
32799124 |
| Submission date |
Nov 12, 2019 |
| Last update date |
Sep 02, 2020 |
| Contact name |
Anita Sveen |
| E-mail(s) |
anita.sveen@rr-research.no
|
| Organization name |
Institute for Cancer Research, Oslo University Hospital
|
| Department |
Department of Molecular Oncology
|
| Street address |
P.O.Box 4953, Nydalen
|
| City |
Oslo |
| ZIP/Postal code |
NO-0424 |
| Country |
Norway |
| |
|
| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
| Samples (12)
|
| GSM4158446 |
Cell line LS513 treated with 100nM talazoparib |
| GSM4158447 |
Cell line LS513 treated with 1000nM talazoparib |
| GSM4158448 |
Cell line LS513 treated with DMSO |
| GSM4158449 |
Cell line SKCO1 treated with 100nM talazoparib |
| GSM4158450 |
Cell line SKCO1 treated with 1000nM talazoparib |
| GSM4158451 |
Cell line SKCO1 treated with DMSO |
| GSM4158452 |
Cell line SNU61 treated with 100nM talazoparib |
| GSM4158453 |
Cell line SNU61 treated with 1000nM talazoparib |
| GSM4158454 |
Cell line SNU61 treated with DMSO |
| GSM4158455 |
Cell line SW1222 treated with 100nM talazoparib |
| GSM4158456 |
Cell line SW1222 treated with 1000nM talazoparib |
| GSM4158457 |
Cell line SW1222 treated with DMSO |
|
| Relations |
| BioProject |
PRJNA589059 |
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