|
| Status |
Public on Dec 07, 2020 |
| Title |
WWOX gene and estrogen receptor interplay in breast cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Other
|
| Summary |
The aim of presented study was to assess the relationship between the presence of estrogen receptor and WWOX gene in breast cancer cell lines.
|
| |
|
| Overall design |
The study was based on estrogen-responsive (MCF7) and estrogen-unresponsive (MDA-MB-231, BT20) cell lines, for which depending on native expression, WWOX gene was either induced by retroviral transfection (MDA-MB-231) or silenced with shRNA (MCF7, BT20), and changes in the phenotype were estrogen stimulated. We have employed nAnT-iCAGE methodology for high-throughput gene expression profiling.
|
| |
|
| Contributor(s) |
Bednarek AK, Pospiech K |
| Citation(s) |
35290621 |
| Submission date |
Nov 14, 2019 |
| Last update date |
Apr 27, 2022 |
| Contact name |
Andrzej K. Bednarek |
| E-mail(s) |
andrzej.bednarek@umed.lodz.pl
|
| Phone |
+48 604583839
|
| Organization name |
Medical University in Lodz
|
| Department |
Department of Molecular Carcinogenesis
|
| Street address |
Zeligowskiego St. 7/9
|
| City |
Lodz |
| ZIP/Postal code |
90-752 |
| Country |
Poland |
| |
|
| Platforms (1) |
|
| Samples (30)
|
|
| Relations |
| BioProject |
PRJNA589614 |
| SRA |
SRP229975 |
Less...
More...