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Series GSE140462 Query DataSets for GSE140462
Status Public on May 28, 2020
Title Multifaceted rewiring of the hepatic lipidome during proliferation and carcinogenesis - PART 2 (Human HCC - "Fatty Liver" background)
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The scope of this project is to study, using state-of-the-art systems biology approaches integrating the changes in metabolomics, lipidomics and transcriptomics, changes in hepatocytes' metabolism occurring in human HCC. We focused on altered metabolic pathways including lipogenesis, fatty acid desaturation, and generation of phosphatidylcholine (PC) occurring in HCC vs. paired HCC-free tissue.
Overall design HCC samples and paired HCC-free tissues were collected during hepatectomy or transplant.
Contributor(s) Hoare M, Allison M, Vacca M, Hall Z, Chiarugi D
Citation(s) 32460431
Submission date Nov 15, 2019
Last update date Sep 23, 2020
Contact name Davide Chiarugi
Organization name WT-MRC Institute of Metabolic Science
Department Metabolic Research Laboratories
Street address Box 289, Addenbrooke’s Hospital
City Cambridge
ZIP/Postal code CB2 0QQ
Country United Kingdom
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (14)
GSM4162226 HCC-FREE2
GSM4162227 HCC-FREE3
GSM4162228 HCC-FREE4
This SubSeries is part of SuperSeries:
GSE140463 Multifaceted rewiring of the hepatic lipidome during proliferation and carcinogenesis
BioProject PRJNA589847
SRA SRP230192

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE140462_RAW.tar 59.2 Mb (http)(custom) TAR (of TAB)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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