|
| Status |
Public on Jun 15, 2020 |
| Title |
Transcriptome profile of Primary Human Lung Fibroblasts (Cystic Fibrosis vs. Non-Cystic Fibrosis) arranged in a 3D model of the connective airways tissue |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The 3D model of the connective airways tissue was obtained by using a specific bottom up approach of tissue engineering allowing to develop 3D tissues featured by the presence of fibroblasts embedded into an endogenous matrix produced by fibroblasts themselves.
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| |
|
| Overall design |
Total RNA was extracted from Cystic Fibrosis and Non-Cystic Fibrosis fibroblasts after 4 weeks of culture of the connective airways tissue in vitro.
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| |
|
| Contributor(s) |
De Cegli R, Imparato G |
| Citation(s) |
32492951 |
| Submission date |
Dec 05, 2019 |
| Last update date |
Sep 14, 2020 |
| Contact name |
Rossella De Cegli |
| E-mail(s) |
decegli@tigem.it
|
| Phone |
08119230692
|
| Organization name |
Tigem
|
| Street address |
Via Campi Flegrei 34
|
| City |
Pozzuoli |
| ZIP/Postal code |
80078 |
| Country |
Italy |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (6)
|
| GSM4205779 |
Normal Human Lung Fibroblasts from the 3D connective airways tissue in vitro, rep1 |
| GSM4205780 |
Normal Human Lung Fibroblasts from the 3D connective airways tissue in vitro, rep2 |
| GSM4205781 |
Normal Human Lung Fibroblasts from the 3D connective airways tissue in vitro, rep3 |
| GSM4205782 |
Disease Human Lung Fibroblasts (Cystic Fibrosis) from the 3D connective airways tissue in vitro, rep1 |
| GSM4205783 |
Disease Human Lung Fibroblasts (Cystic Fibrosis) from the 3D connective airways tissue in vitro, rep2 |
| GSM4205784 |
Disease Human Lung Fibroblasts (Cystic Fibrosis) from the 3D connective airways tissue in vitro, rep3 |
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| This SubSeries is part of SuperSeries: |
| GSE141537 |
Transcriptome profile of Primary Human Lung Fibroblasts (Cystic Fibrosis vs. Non-Cystic Fibrosis) |
|
| Relations |
| BioProject |
PRJNA593832 |
| SRA |
SRP234890 |
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