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| Status |
Public on Apr 06, 2020 |
| Title |
Chronic rare DUX4 expression in mouse drives transcriptional similarities to human FSHD in whole muscle and fibroadiopgenic progenitors |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-seq data was obtained on various samples from the iDUX4pA mouse model for FSHD and from control WT littermates.
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| Overall design |
RNA-seq was performed on whole muscle, as well as sorted endothelial cells and fibroadipogenic progenitors at early and late time points in the course of the disease.
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| Contributor(s) |
Bosnakovski D, Yuan C, Kyba M |
| Citation |
Carlo Serra and Kathryn R Wagner. It's not all about muscle: fibroadipogenic progenitors contribute to facioscapulohumeral muscular dystrophy. J Clin Invest 2020. doi:10.1172/JCI136133
|
| Submission date |
Dec 06, 2019 |
| Last update date |
Apr 09, 2020 |
| Contact name |
Michael Kyba |
| Organization name |
University of Minnesota
|
| Street address |
2231 6th St SE
|
| City |
Minneapolis |
| State/province |
MN |
| ZIP/Postal code |
55455 |
| Country |
USA |
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| Platforms (2) |
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| Samples (32)
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| Relations |
| BioProject |
PRJNA593958 |
| SRA |
SRP234928 |
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