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Series GSE141669 Query DataSets for GSE141669
Status Public on Apr 15, 2021
Title Genomic landscapes of VEGF family members in endothelial cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Role of novel long intergenic (lincRNA) and enhancer RNAs (eRNAs) in the regulation of vascular endothelial growth factors (VEGFs), in endothelial cells.
 
Overall design Integration of different sequencing techniques (GRO-Seq, Hi-C and Chip-Seq) in primary endothelial cells (HUVEC), to identify lincRNA and eRNA. Knock out validation studies with CRISPR/Cas9, followed by RNA-Seq in EA.hy926
 
Contributor(s) Kaikkonen-Määttä M, Mushimiyimana I, Tomas Bosch V, Niskanen H, Downes N, Moreau P, Laram-Karam N, Ylä-Herttuala S
Citation(s) 33875575
Submission date Dec 09, 2019
Last update date Jul 15, 2021
Contact name Minna Kaikkonen-Määttä
Organization name A. I. Virtanen Institute
Street address P. O. Box 1627
City Kuopio
ZIP/Postal code 70721
Country Finland
 
Platforms (1)
GPL21697 NextSeq 550 (Homo sapiens)
Samples (10)
GSM4210857 EA.hy.RNA.AlincRNA.rep1
GSM4210858 EA.hy.RNA.AlincRNA.rep2
GSM4210859 EA.hy.RNA.AlincRNA.rep3
Relations
BioProject PRJNA594338
SRA SRP235266

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE141669_RAW.tar 776.5 Mb (http)(custom) TAR (of BEDGRAPH)
GSE141669_RNA-Seq_VEGFA_lincKO_VEGFC_lincKO_RPKM.txt.gz 3.9 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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