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| Status |
Public on May 18, 2020 |
| Title |
Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Actinic keratosis is a common skin disease that may progress to invasive squamous cell carcinoma. Ingenol mebutate has demonstrated efficacy in field treatment of actinic keratosis. However, molecular mechanisms on ingenol mebutate response are not yet fully understood.
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| |
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| Overall design |
Single-center, single-arm, prospective observational study conducted in Hospital del Mar in Barcelona from April 2016 to April 2018, to evaluate mRNA expression profile of actinic keratoses before and after treatment with ingenol mebutate gel.
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| |
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| Contributor(s) |
Segura S, Toll A, Gadea A, Nonell L, Andrades E, Sánchez S, Pujol R, Hernández-Muñoz I |
| Citation(s) |
32413042 |
| Submission date |
Dec 16, 2019 |
| Last update date |
Oct 19, 2023 |
| Contact name |
Júlia Perera-Bel |
| E-mail(s) |
mardata-bu@researchmar.net
|
| Organization name |
Hospital del Mar Research Institute
|
| Department |
MARData-BU
|
| Street address |
Doctor Aiguader, 88
|
| City |
Barcelona |
| ZIP/Postal code |
08003 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
|
| Samples (60)
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| Relations |
| BioProject |
PRJNA595920 |
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