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Series GSE142636 Query DataSets for GSE142636
Status Public on Aug 13, 2020
Title Transcriptome of Human Primary Corneal Endothelial Cells with SLC4A11 deficiency
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Mutations in the solute-linked carrier family 4 member 11 (SLC4A11) gene are associated with several corneal endothelial dystrophies, in all of which visually significant cornea edema may require corneal transplantation. To elucidate the pathogenesis of SLC4A11 associated corneal endothelial dystrophies, we analyzed the transcriptome of SLC4A11 knock-down primary human corneal endothelium (SLC4A11 KD pHCEnC) and scrambled RNA treated pHCEnC as controls.
 
Overall design 3 KD vs 3 CTRL
 
Contributor(s) Zhang W, Frausto R, Aldave A
Citation(s) 32721020
Submission date Dec 26, 2019
Last update date Aug 13, 2020
Contact name Wenlin Zhang
E-mail(s) w.zhang@jsei.ucla.edu
Organization name UCLA, Jules Stein Eye Institute
Street address 200 Stein Plaza, Dserc 3-143
City Los Angeles
State/province CA
ZIP/Postal code 90095
Country USA
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (6)
GSM4233272 scRNA 1
GSM4233273 scRNA 2
GSM4233274 scRNA 3
Relations
BioProject PRJNA597782
SRA SRP238854

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE142636_pHCEnC_KDvsWT.txt.gz 874.0 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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