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| Status |
Public on Feb 26, 2020 |
| Title |
Analysis of gene expression in lung adenocarcinoma cells following over-expression of miR-30a-5p or miR-30a-3p |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-sequencing was performed to gain insight into the transcriptome-wide molecular changes induced by miR-30a-5p or miR-30a-3p over-expression in lung adenocarcinoma cells. Following transfection of miR-30a-5p or miR-30a-3p miRNA mimic or control RNA, RNA-sequencing was performed. This high-throughput data revealed elevated expression of both miR-30a-5p and miR-30a-3p reduced the expression of genes and pathways known to induce proliferation and movement in lung adenocarcinoma cells.
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| |
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| Overall design |
miR-30a-5p or miR-30a-3p was transfected in lung adenocarcinoma cells and gene expression profiles were generated using RNA-sequencing.
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| Contributor(s) |
Eischen CM, Mitra R |
| Citation(s) |
32080184 |
| Submission date |
Dec 28, 2019 |
| Last update date |
Aug 17, 2022 |
| Contact name |
Ramkrishna Mitra |
| E-mail(s) |
ramkrishna.mitra@jefferson.edu
|
| Organization name |
Thomas Jefferson University
|
| Street address |
233 S 10th street
|
| City |
Philadelphia |
| State/province |
Pennsylvania |
| ZIP/Postal code |
19107 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA597999 |
| SRA |
SRP238971 |
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