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| Status |
Public on Jan 22, 2009 |
| Title |
A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We identify inducible binding of the transcription factor Oct1 to numerous targets following exposure to hydrogen peroxide.
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| Overall design |
Oct1 bound ChIP fragments were sequenced in the presence and absence of H2O2 exposure using HeLa cells. Both 26 and 36bp reads were generated.
Each processed file contains a list of genomic regions (NCBI 36.1, H_sapiens_Mar_2006, hg18) enriched for Oct1 binding.
These files were generated by running the EnrichedRegionMaker on ScanSeqs window scored data, see http://useq.sourceforge.net/ .
Adjacent and overlapping windows with a q-value FDR of 0.0001 were joined into larger enriched regions.
The best scoring window's scores are used to represent the enriched region.
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| Contributor(s) |
Kang J, Tantin D |
| Citation(s) |
19171782 |
| Submission date |
Jan 05, 2009 |
| Last update date |
May 15, 2019 |
| Contact name |
Dean Tantin |
| E-mail(s) |
dean.tantin@path.utah.edu
|
| Phone |
(801) 587-3035
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| Organization name |
University of Utah
|
| Department |
Department of Pathology
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| Street address |
15 North Medical Drive East
|
| City |
Salt Lake City |
| State/province |
UT |
| ZIP/Postal code |
84112 |
| Country |
USA |
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| Platforms (1) |
| GPL9115 |
Illumina Genome Analyzer II (Homo sapiens) |
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| Samples (2) |
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| Relations |
| SRA |
SRP000635 |
| BioProject |
PRJNA111253 |
