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Series GSE1432 Query DataSets for GSE1432
Status Public on Dec 25, 2004
Title Transcriptional Response of Human Microglial Cells to Interferon-gamma
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Microglial cells are resident macrophages in the central nervous system (CNS) and play a pivotal role in the innate and adaptive immune responses against microbial infections. The immune functions of microglia are regulated by a milieu of cytokines including interferon (IFN)-gamma. We here performed a series of experiments to acertain the transcriptional profile of human fetal microglial cells at 1, 6, and 24 h after IFN-gamma treatment. Primary human microglial cells were either untreated or treated with 200u/ml IFN-gamma. Affymetrix U133A chips were utilized. Four different tissue samples (B18, O, W, and Y20) were analyzed at the three time points.
Keywords = Microglia
Keywords = Interferon-gamma
Keywords: time-course
 
 
Contributor(s) Rock RB, Hu S, Deshpande A, Munir S, May B, Peterson PK, Kapur V
Citation(s) 16163375
Submission date May 25, 2004
Last update date Aug 10, 2018
Contact name Robert Bryan Rock
E-mail(s) brock1007@msn.com
Phone 612-624-9996
Organization name University of Minnesota
Street address
City Minneapolis
State/province MN
ZIP/Postal code 55455
Country USA
 
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (24)
GSM23887 IFNG Microglia Sample B18 1hr
GSM23893 IFNG Microglia Sample O 1hr
GSM23895 IFNG Microglia Sample W 1hr
Relations
BioProject PRJNA89967

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