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Series GSE144831 Query DataSets for GSE144831
Status Public on Aug 20, 2020
Title Cardiac-tbx20 overexpression enhances heart regeneration by promoting cardiomyocytes dedifferentiation and endocardial activation
Organism Danio rerio
Experiment type Expression profiling by high throughput sequencing
Summary The goal of this study is to understand the function of cardiac tbx20 during heart regeneration. By high-throughput sequencing, molecular variations of tbx20-cardiac specific inducing heart in response to heart injury compared with control hearts were demonstrated. We collected the injured heart apex tissue at 7 days post injury and sequenced the transcriptome.
 
Overall design RNA was extracted from ventricular apical portions at 7 days post injury from control hearts and tbx20-cardiac-specific inducing hearts. Tissue from 6-8 zebrafish were collected in each control group or cardiac-tbx20-overexpressing group, three replications were carried out.
 
Contributor(s) Fang Y, Lai KS, Tao W, Zhong TP
Citation(s) 32850848
https://0-doi-org.brum.beds.ac.uk/10.3389/fcell.2020.00738
Submission date Feb 06, 2020
Last update date Aug 31, 2020
Contact name Tao Peter Zhong
E-mail(s) taozhong@fudan.edu.cn, tzhong@bio.ecnu.edu.cn
Organization name Fudan University
Department School of Life Sciences
Lab State Key Laboratory of Genetic Engineering
Street address No.2005, Songhu Road
City Shanghai
State/province China
ZIP/Postal code 200438
Country China
 
Platforms (1)
GPL14875 Illumina HiSeq 2000 (Danio rerio)
Samples (6)
GSM4298940 Ctrl_01
GSM4298941 Ctrl_02
GSM4298942 Ctrl_03
Relations
BioProject PRJNA605096
SRA SRP247485

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE144831_all.fpkm_anno.txt.gz 1.4 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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