|
| Status |
Public on Feb 16, 2009 |
| Title |
ETS2, ERG promote megakaryopoiesis, synergize with alterations in GATA1 to immortalize hematopoietic progenitor cells |
| Platform organism |
Mus musculus |
| Sample organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Serial replated GFP + lineage negative cells from Gata1deltaneodeltaHS fetal liver hematopoietic progenitors for 4 generations in methocult M3234 under megakaryocyte promoting conditions, IL3, TPO, IL6, and IL11. Cells were subject to retro-viral infection with MIGR1GFP, MIGR1ETS2, MIGR1ERG, and MIGR1FLI1.
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| |
|
| Overall design |
Comparison of gene expression profile for GFP + immortalized MIGR1-GFP Gata1deltaneodeltaHS fetal liver progenitors to that of GFP+ Gata1deltaneodeltaHS MIGR1-ETS2, MIGR1-ERG, and MIGR1FLI1 fetal liver progenitors
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| |
|
| Citation(s) |
19168790 |
| Submission date |
Jan 21, 2009 |
| Last update date |
Jan 18, 2013 |
| Contact name |
monika stankiewicz |
| Organization name |
Northwestern University
|
| Department |
Hematology/Oncology
|
| Lab |
Crispino
|
| Street address |
303 E. Superior St. Lurie Bldg 5-250
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60611 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6103 |
Illumina mouseRef-8 v1.1 expression beadchip |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA111647 |
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