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Status |
Public on Feb 16, 2009 |
Title |
ETS2, ERG promote megakaryopoiesis, synergize with alterations in GATA1 to immortalize hematopoietic progenitor cells |
Platform organism |
Mus musculus |
Sample organisms |
Homo sapiens; Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Serial replated GFP + lineage negative cells from Gata1deltaneodeltaHS fetal liver hematopoietic progenitors for 4 generations in methocult M3234 under megakaryocyte promoting conditions, IL3, TPO, IL6, and IL11. Cells were subject to retro-viral infection with MIGR1GFP, MIGR1ETS2, MIGR1ERG, and MIGR1FLI1.
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Overall design |
Comparison of gene expression profile for GFP + immortalized MIGR1-GFP Gata1deltaneodeltaHS fetal liver progenitors to that of GFP+ Gata1deltaneodeltaHS MIGR1-ETS2, MIGR1-ERG, and MIGR1FLI1 fetal liver progenitors
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Citation(s) |
19168790 |
Submission date |
Jan 21, 2009 |
Last update date |
Jan 18, 2013 |
Contact name |
monika stankiewicz |
Organization name |
Northwestern University
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Department |
Hematology/Oncology
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Lab |
Crispino
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Street address |
303 E. Superior St. Lurie Bldg 5-250
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City |
Chicago |
State/province |
IL |
ZIP/Postal code |
60611 |
Country |
USA |
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Platforms (1) |
GPL6103 |
Illumina mouseRef-8 v1.1 expression beadchip |
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Samples (14)
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Relations |
BioProject |
PRJNA111647 |