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| Status |
Public on Jan 19, 2021 |
| Title |
miRNA expression profiling in a murine model of KrasG12D induced CMML-like MPD |
| Platform organism |
synthetic construct |
| Sample organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Mx1-Cre/KrasG12D mice were injected with pIpC to induce a myeloproliferative disease resembling human chronic myelomonocytic leukemia (CMML-like MPD). When the disease was fully developed, CD11b-/Ly6G-/c-Kit+ hematopoietic stem and progenitor cells (HSPCs) were isolated and subjected to miR-microarray expression profiling. pIpC-injected CD11b-/Ly6G-/c-Kit+ HSPCs of age matched wildytpe control mice were used as controls.
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| Overall design |
n=4 (KrasG12D vs. Wt)
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| Contributor(s) |
Berg JL, Zebisch A |
| Citation(s) |
33407852 |
| Submission date |
Feb 11, 2020 |
| Last update date |
Jan 19, 2021 |
| Contact name |
Karin Wagner |
| E-mail(s) |
kar.wagner@medunigraz.at
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| Organization name |
Medical University Graz
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| Department |
Molecular Biology
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| Street address |
Stiftingtalstrasse 24
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| City |
Graz |
| State/province |
Styria |
| ZIP/Postal code |
8010 |
| Country |
Austria |
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| Platforms (1) |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA605975 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE145083_RAW.tar |
5.4 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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