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Series GSE14546 Query DataSets for GSE14546
Status Public on Dec 28, 2009
Title Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension
Platform organism Bos taurus
Sample organisms Bos taurus; Ovis aries
Experiment type Expression profiling by array
Summary The loss of PPARγ is found to be associated with the development of pulmonary hypertension (PH). We hypothesize that PPARγ inhibition induced gene expression changes may underscore the endothelial dysfunction in the disease process.
We utilized microarray analysis to determine gene expression changes in PPARγ inhibited ovine PAECs.
 
Overall design Ovine PAECs were treated with vehicle (DMSO) or GW9662 (5μM) for 24hrs, and total RNA was extracted for microarray analysis.
 
Contributor(s) Tian J, Smith A, Nechtman J, Podolsky R, Aggarwal S, Kumar S, Eglaish M, Oishi P, Görlach A, Fratz S, Hess J, Catravas J, Verin J, Fineman J, She J, Black SM
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Submission date Jan 23, 2009
Last update date Mar 06, 2020
Contact name Jing Tian
E-mail(s) jtian@mcg.edu
Phone 706-721-0074
Organization name Medical College of Georgia
Department Vascular Biology Center
Lab Lab of Stephen M. Black
Street address 1459 Laney Walker BLVD
City Augusta
State/province GA
ZIP/Postal code 30912
Country USA
 
Platforms (1)
GPL2112 [Bovine] Affymetrix Bovine Genome Array
Samples (15)
GSM363864 Bovine Control 1
GSM363865 Bovine Control 2
GSM363866 Bovine Control 3
Relations
BioProject PRJNA111639

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14546_RAW.tar 26.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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