|
| Status |
Public on Mar 09, 2021 |
| Title |
Distinct cardiac transcriptomic clustering in titin and lamin a/c-associated dilated cardiomyopathy patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA profiles strongly differ in TTNtv and LMNA-mutated DCM patients, despite clinical similarities as other pathogenic variant carriers such as RBM20 and MYH7, suggesting a specific genetic effect on the cardiac transcriptome in addition to the effect of the clinical component.
|
| |
|
| Overall design |
Comparing RNA-seq profiles of genetic DCM patients
|
| |
|
| Contributor(s) |
Verdonschot JA, Derks KW |
| Citation(s) |
32955937, 36631531 |
| Submission date |
Mar 09, 2020 |
| Last update date |
Jan 25, 2023 |
| Contact name |
Kasper Derks |
| E-mail(s) |
kasper.derks@mumc.nl
|
| Organization name |
Maastricht University Medical Center
|
| Department |
Clinical Genetics
|
| Street address |
P. Debyelaan 25
|
| City |
Maastricht |
| State/province |
Limburg |
| ZIP/Postal code |
6229 HX |
| Country |
Netherlands |
| |
|
| Platforms (1) |
|
| Samples (29)
|
|
| Relations |
| BioProject |
PRJNA611524 |
| SRA |
SRP252042 |
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