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| Status |
Public on Aug 25, 2021 |
| Title |
Gene expression in the F1 and F2 mouse hippocampus with intrauterine hyperglycemia exposure |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Studies on human and animals suggest associations between gestational diabetes mellitus (GDM) with impaired cognitive performance in offspring. Using a mouse model of diabetes during pregnancy, we found that intrauterine hyperglycemia exposure resulted in memory impairment in both the first filial (F1) males and the second filial (F2) males from the F1 male offspring. The effects of intrauterine hyperglycemia exposure on F1 and F2 hippocampus gene expression were also examined.
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| Overall design |
Hippocampus, male, 16 weeks old. Three groups, F1 offsprings of GDM (F1-GDM) ，F2 offsprings of GDM (F2-GDM) and Control, with 5 replicates per group.
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| Contributor(s) |
Zou K, Ding G |
| Citation(s) |
34417446 |
| Submission date |
Mar 16, 2020 |
| Last update date |
Aug 26, 2021 |
| Contact name |
Kexin Zou |
| Organization name |
Shanghai Jiao Tong University School of Medicine
|
| Street address |
145 Guangyuan Rd
|
| City |
Shanghai |
| ZIP/Postal code |
200030 |
| Country |
China |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA612832 |
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