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| Status |
Public on Aug 19, 2020 |
| Title |
Genome wide H3k27ac modification changes in Wild Type PC9 cells and MED13L knocking-down PC9 cells [H3K27ac ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Silencing of MED13L impairs Mediator-regulated chromatin H3K27ac modification in NSCLC. Here, we performed H3K27ac ChIP-seq to investigate impacts of miR-4497 or knocking-down MED13L on chromatin H3K27ac modification in NSCLC PC9 cells.
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| |
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| Overall design |
Four samples were examined: PC9 cells transfected with miR-4497 mimics, si13L-1, si13L-2 or negtive control RNA.
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| |
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| Contributor(s) |
Yang M, Zhang N |
| Citation(s) |
32802198 |
| Submission date |
Mar 17, 2020 |
| Last update date |
Aug 19, 2020 |
| Contact name |
Nasha Zhang |
| E-mail(s) |
wownseva@126.com
|
| Organization name |
Shandong Cancer Hospital and Institute
|
| Department |
Cancer Research Center
|
| Lab |
Shandong Provincial Key Laboratory of Radiation Oncology
|
| Street address |
No. 440 Jiyan Road
|
| City |
Jinan |
| State/province |
Shandong |
| ZIP/Postal code |
250117 |
| Country |
China |
| |
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| Platforms (1) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA613059 |
| SRA |
SRP253100 |
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