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Series GSE147318 Query DataSets for GSE147318
Status Public on Sep 01, 2020
Title Saliva cell type DNA methylation reference panel for epidemiology studies in children
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary We profiled the DNA methylation of saliva cell types, to develop a tool for epidemiologic studies. Saliva was collected from 22 children, 21 participants with samples usable for DNA methylation, and sorted into immune and epithelial cells, using size exclusion filtration and magnetic bead sorting. DNA methylation was measured using the Illumina MethylationEPIC BeadChip. Saliva immune and epithelial cells have distinct DNA methylation profiles, which can influence whole saliva epidemiologic measures.
 
Overall design 60 samples from 21 individuals: 18 large cell fractions, 20 CD45+ cell fractions, 18 whole saliva, 4 Oragene kit
 
Contributor(s) Middleton LM, Dou J, Fisher J, Heiss JA, Just AC, Faul J, Ware EB, Mitchell C, Colacino JA, Bakulski KM
Citation(s) 33588693
Submission date Mar 20, 2020
Last update date Mar 02, 2022
Contact name Kelly Bakulski
E-mail(s) bakulski@umich.edu
Organization name University of Michigan
Department Department of Epidemiology
Street address 1415 Washington Heights
City Ann Arbor
State/province MI
ZIP/Postal code 48109
Country USA
 
Platforms (1)
GPL21145 Infinium MethylationEPIC
Samples (60)
GSM4425719 saliva CD45pos DNA from participant 11
GSM4425720 saliva whole DNA from participant 6
GSM4425721 saliva CD45pos DNA from participant 12
Relations
BioProject PRJNA613722

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE147318_RAW.tar 991.0 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table
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