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Status |
Public on May 07, 2021 |
Title |
Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We report the transcriptomes of single cells isolated from whole skin of wild type B6 male mice fed a standard or 60% high fat diet 48-hours after mock- or S. aureus-infection.
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Overall design |
Wild type B6 male mice fed a standard or 60% high fat diet ad libitum were mock- or S. aureus-infected. Two days post-infection whole skin samples were collected and processed for 3'-end single cell RNA-sequencing.
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Contributor(s) |
Guerrero-Juarez CF, Zhang L, Plikus M, Gallo RL |
Citation(s) |
33472955 |
Submission date |
May 17, 2020 |
Last update date |
May 09, 2021 |
Contact name |
Maksim V Plikus |
E-mail(s) |
plikus@uci.edu
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Phone |
949-824-1260
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Organization name |
University of California, Irvine
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Department |
Developmental and Cell Biology
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Street address |
845 Health Sciences Road
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City |
Irvine |
State/province |
California |
ZIP/Postal code |
92697 |
Country |
USA |
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Platforms (1) |
GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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Samples (4)
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Relations |
BioProject |
PRJNA633394 |
SRA |
SRP262059 |