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Series GSE15163 Query DataSets for GSE15163
Status Public on Mar 10, 2009
Title Gene expression data from primate postnatal brain development - superior frontal gyrus
Platform organism Homo sapiens
Sample organisms Macaca mulatta; Pan troglodytes; Homo sapiens
Experiment type Expression profiling by array
Summary In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain size and the rise of human-specific cognitive traits .
We measured the timing of gene expression changes in the superior frontal gyrus region of the brains of humans, chimpanzees, and rhesus macaques throughout postnatal development.

Keywords: Age series
 
Overall design Human, chimpanzee and rhesus macaque post-mortem brain samples from the superior frontal gyrus region of the prefrontal cortex were collected. The age ranges of the individuals in all three species covered the respective species' postnatal maturation period from infancy to adulthood. RNA extracted from the dissected tissue was hybridized to Affymetrix® Human Gene 1.0 ST arrays.
Web link http://www.picb.ac.cn/Comparative/
 
Contributor(s) Somel M, Zhen Y, Guo S, Bahn S, Webster MJ, Weickert CS, Lachmann M, Pääbo S, Khaitovich P
Citation(s) 19307592
Submission date Mar 09, 2009
Last update date Jul 26, 2018
Contact name Mehmet Somel
E-mail(s) somel@eva.mpg.de
Phone +49-(0)341-3550-530
Fax +49-(0)341-3550-555
Organization name Max Planck Institute for Evolutionary Anthropology
Department Evolutionary Genetics
Street address Deutscher Platz 6
City Leipzig
ZIP/Postal code D-04103
Country Germany
 
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (27)
GSM378696 Human-superior frontal gyrus-1 day old
GSM378697 Human-superior frontal gyrus-4 days old
GSM378698 Human-superior frontal gyrus-0.1 years old
Relations
BioProject PRJNA114937

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE15163_HuGene-1_0-st_h18c2r2umask_maskedprobes.tsv.gz 5.2 Mb (ftp)(http) TSV
GSE15163_RAW.tar 90.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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