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Series GSE151800 Query DataSets for GSE151800
Status Public on Jun 06, 2021
Title Gene expression data from memory Rictor-/- and WT Tfh and Th1 cells in LCMV acute infection
Organism Mus musculus
Experiment type Expression profiling by array
Summary Microarray experiments were performed to demonstrate the transcriptome changes due to Rictor deficiency in memory follicular T helper (Tfh) and Type 1 T helper (Th1) cells.
These data revealed that the immunological memory formation and persistance associated genes are changed in Rictor-null memory Tfh and Th1 cells, indicating that Rictor is essential for memory CD4 T cell pool.
 
Overall design Polyclonal memory Rictor-null and WT Tfh and Th1 cells (2 samples per group, each sample was pooled from at least 10 mice) were sorted at day 60-post LCMV Armstrong infection, followed by total RNA extracted and sent to microarray analysis.
 
Contributor(s) Ye L, Wang Y, Hao Y, Tian Q
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jun 04, 2020
Last update date Jun 07, 2021
Contact name Yifei Wang
E-mail(s) yfwangsophia@163.com
Phone 86-15088062080
Organization name Third Military Medical University
Department Institute of Immunology
Street address Gaotanya Street
City Chongqing
ZIP/Postal code 400038
Country China
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (8)
GSM4591130 KOTFH-1: Rictor-null Tfh, biological rep.1
GSM4591131 KOTFH-2: Rictor-null Tfh, biological rep.2
GSM4591132 WTTFH-1: Wild-type Tfh, biological rep.1
Relations
BioProject PRJNA637301

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE151800_RAW.tar 26.4 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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