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Series GSE15354 Query DataSets for GSE15354
Status Public on May 01, 2009
Title Cardiac left ventricles of 12 week-old male C57BL/6J and C57BL/6J-chrY<A/J/NaJ> mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary We have reported previously that when chromosome Y (chrY) from the mouse strain C57BL/6J (abbreviated as B) was substituted for that of A/J mice (ChrY<A>), cardiomyocytes from the resulting 'chromosome substitution' C57BL/6J-chrY<A> strain (abbreviated as B.Y) were smaller than that of their C57BL/6J counterparts. In reverse, when chrY<A> from A/J mice was substituted for that of chrY<B>, cardiomyocytes from the resulting A/J-chrY<C57> strain were larger than in their A/J counterparts. We further used these strains (B and the consomic B.Y) to test whether the origin of chrY could also be linked to differences in the profile of gene expression in their cardiac left ventricles in adult mice where either sham surgery (intact animals) or castration has been performed at 3-4 weeks of age..
 
Overall design Samples from 4 different mice were used in each group. For hybridization, probes generated from samples were randomized on 2 different Illumina MouseRef v2.0 BeadChips.
 
Contributor(s) Deschepper CF, Llamas B, Verdugo RA, Churchill GA
Citation(s) 19351403
Submission date Mar 23, 2009
Last update date Jun 14, 2018
Contact name Christian F Deschepper
E-mail(s) deschec@ircm.qc.ca
Phone 514 987 5759
Fax 514 987 5585
Organization name IRCM
Lab Cardiovascular biology
Street address 110 ave des Pins Ouest
City Montreal
State/province QC
ZIP/Postal code H2W1R7
Country Canada
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (16)
GSM385538 CDR017
GSM385539 CDR025
GSM385540 CDR021
Relations
BioProject PRJNA115769

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE15354_RAW.tar 3.1 Mb (http)(custom) TAR
GSE15354_raw.txt 11.4 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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