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| Status |
Public on Jan 01, 2021 |
| Title |
High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We sought to examine whether directly dietary fiber application to offspring could also reverse the behavioral and neurobiological deficits characteristic of MHFD offspring. RNA-sequencing (RNA-seq) on mice hippocampus were performed in order to identify the key biological processes and pathways regulated by dietary fiber.
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| Overall design |
8 CD-C mice,8 CD-F mice,8 FD-C mice, 8 FFD-C mice, 9 HFD-C mice, 8 HFD-F mice
|
| Web link |
https://0-doi-org.brum.beds.ac.uk/10.1016/j.cmet.2021.02.002
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| |
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| Contributor(s) |
Liu X, Jin X |
| Citation(s) |
33651981 |
| Submission date |
Jul 14, 2020 |
| Last update date |
Apr 06, 2021 |
| Contact name |
Jin Xin |
| E-mail(s) |
jinxin1@genomics.cn
|
| Phone |
13419631327
|
| Organization name |
BGI
|
| Street address |
Beishan road
|
| City |
Shenzhen |
| State/province |
Guangdong |
| ZIP/Postal code |
518120 |
| Country |
China |
| |
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| Platforms (1) |
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| Samples (49)
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| Relations |
| BioProject |
PRJNA646250 |
| SRA |
SRP271814 |
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