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| Status |
Public on Oct 13, 2020 |
| Title |
Widespread traces of lytic KSHV in primary effusion lymphoma at single-cell resolution |
| Organisms |
Homo sapiens; human gammaherpesvirus 4; Human gammaherpesvirus 8 |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Cancer cells of primary effusion lymphoma (PEL) often contain both Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). We measured the interplay of human, KSHV, and EBV transcription in a cell culture model of PEL using single-cell RNA sequencing. The data detect widespread trace expression of lytic KSHV genes.
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| Overall design |
Single-cell RNA-seq transcriptomes of BC-1 primary effusion lymphoma cells
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| Contributor(s) |
Rondeau NC, Finlayson MO, Miranda JL |
| Citation(s) |
33154001 |
| Submission date |
Jul 22, 2020 |
| Last update date |
Nov 24, 2020 |
| Contact name |
JJ Miranda |
| E-mail(s) |
jmiranda@barnard.edu
|
| Organization name |
Barnard College, Columbia University
|
| Street address |
3009 Broadway
|
| City |
New York |
| ZIP/Postal code |
10027 |
| Country |
USA |
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| Platforms (1) |
| GPL28902 |
Illumina NovaSeq 6000 (Homo sapiens; Human gammaherpesvirus 4; Human gammaherpesvirus 8) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA647855 |
| SRA |
SRP273071 |
