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| Status |
Public on Apr 04, 2009 |
| Title |
Expression data from uterine endometrial tissues of Holstein-Friesian cows on days 14-16 after calving |
| Organism |
Bos taurus |
| Experiment type |
Expression profiling by array
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| Summary |
Most dairy cows suffer uterine microbial contamination postpartum. Persistent endometritis often develops, associated with reduced fertility. We used a model of differential feeding and milking regimes to produce cows in differing negative energy balance (NEB) status in early lactation.
We used Affymetrix GeneChipÒ Bovine Genome Array to investigate the global gene expression underlying negative energy balance and to identify the significantly differentially expressed genes during this process.
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| Overall design |
We investigate the differences of gene expression profiles in uterine endometrial tissues between the cows with mild and severe negative energy balance.
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| Contributor(s) |
Wathes DC, Cheng Z, Chowdhury W, Fenwick MA, Fitzpatrick R, Morris DG, Patton J, Murphy JJ |
| Citation(s) |
19567787, 26479384 |
| Submission date |
Apr 03, 2009 |
| Last update date |
Jun 07, 2019 |
| Contact name |
Zhangrui Cheng |
| E-mail(s) |
zcheng@rvc.ac.uk
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| Phone |
01707666663
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| Organization name |
Royal Veterinary College
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| Department |
Production and Population Health
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| Lab |
Reproduction
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| Street address |
Hawkshead Lane
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| City |
Hatfield |
| State/province |
Hertfordshire |
| ZIP/Postal code |
AL9 7TA |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL2112 |
[Bovine] Affymetrix Bovine Genome Array |
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| Samples (11)
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| GSM389356 |
Endometrium, mild negative energy balance_UCIC109B |
| GSM389357 |
Endometrium, mild negative energy balance_UCIC245 |
| GSM389358 |
Endometrium, mild negative energy balance_UCIC330B |
| GSM389359 |
Endometrium, mild negative energy balance_UCIC3110 |
| GSM389360 |
Endometrium, mild negative energy balance_UCIC1106 |
| GSM389361 |
Endometrium, severe negative energy balance_UCIC11 |
| GSM389362 |
Endometrium, severe negative energy balance_UCIC51 |
| GSM389363 |
Endometrium, severe negative energy balance_UCIC214 |
| GSM389364 |
Endometrium, severe negative energy balance_UCIC231 |
| GSM389365 |
Endometrium, severe negative energy balance_UCIC2463 |
| GSM389366 |
Endometrium, severe negative energy balance_UCIC3156 |
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| Relations |
| BioProject |
PRJNA115979 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE15544_RAW.tar |
34.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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