|
| Status |
Public on Oct 19, 2020 |
| Title |
Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis [RNA-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Super enhancer in liver propagates inflammatory signaling by super enhancer-mediatedinducing chemokine expression and is the therapeutic potential of BET inhibition in Alcoholic hepatitis(AH) treatment.
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| |
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| Overall design |
For human liver RNA-Seq and ChIP-Seq analyses, human liver explants from 6 patients with AH were procured at the time of liver transplant surgery. 4 control patients with no history of chronic liver diseases undergoing liver resection for other causes were obtained to serve as controls.
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| |
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| Contributor(s) |
Shah VH, Cao S, Liu M |
| Citation missing |
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| Submission date |
Aug 08, 2020 |
| Last update date |
Oct 19, 2020 |
| Contact name |
Aditya Bhagwate |
| E-mail(s) |
bhagwate.adityavijay@mayo.edu
|
| Organization name |
Mayo Clinic
|
| Street address |
200 1st Street SW
|
| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
55905 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
| Samples (9)
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| This SubSeries is part of SuperSeries: |
| GSE155926 |
Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis |
|
| Relations |
| BioProject |
PRJNA656197 |
| SRA |
SRP276921 |
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