|
| Status |
Public on Aug 27, 2020 |
| Title |
Transcriptional profiling of hepatocyte, reprogrammed hepatocyte, and biliary cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Following liver injury, a subset of hepatocytes adopt features of biliary epithelial cells (BECs) in a process known as biliary reprogramming. The aim of this study is to elucidate the molecular events accompanying this dramatic shift in cellular identity. Wild type hepatocytes, wild type biliary cells, DDC-treated hepatocytes, DDC-treated biliary cells, and DDC-treated reprogrammed cells were isolated by FACS, RNA isolated, and sequenced.
|
| |
|
| Overall design |
Transcriptional profiling of liver cell populations by RNA-seq in control and DDC-treated mice
|
| |
|
| Contributor(s) |
Merrell A, Li J, Stanger B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 26, 2020 |
| Last update date |
Aug 28, 2020 |
| Contact name |
Jinyang Li |
| E-mail(s) |
jli05@rockefeller.edu
|
| Phone |
2155885072
|
| Organization name |
The Rockefeller University
|
| Lab |
Daniel Mucida Lab
|
| Street address |
1230 York Ave
|
| City |
New York |
| State/province |
New York |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (15)
|
|
| Relations |
| BioProject |
PRJNA659487 |
| SRA |
SRP279021 |
Less...
More...